Suppose that guidelines for this same drug, with the same elimination rate and effective volume of...

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Suppose that guidelines for this same drug, with the same elimination rate and effective volume of 25 L, instruct a maximum concentration of 22.5 mg/L and that a concentration of 10 mg/L should be maintained for the drug to be effective. The drug manufacturer suggests that doses of 250 mg should be repeated every 8 hours. Is this dosing regime consistent with the guidelines, and if not, why not? (7 marks) Suppose that guidelines for this same drug, with the same elimination rate and effective volume of 25 L, instruct a maximum concentration of 22.5 mg/L and that a concentration of 10 mg/L should be maintained for the drug to be effective. The drug manufacturer suggests that doses of 250 mg should be repeated every 8 hours. Is this dosing regime consistent with the guidelines, and if not, why not? (7 marks)

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Plasma levels of the drug should be maintained within ... View the full answer