The batch fermentation of glucose to glutamic acid using Brevibacterium divaricatum is described in detail in US patent 2,978,384. In Example I in the patent a 10.5 wt% glucose feed was fermented for 72 hours at 30 °C, giving 33.5 wt% glutamic acid yield on glucose. What annual production of glutamic acid can be achieved in a batch fermentation plant that has four 10,000 liter reactors? The reactors have jackets that can be used for steam heating or water cooling, but no internal coils.

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Each batch run last for 3 days 72 hours consists of 105 wt glucose in feed end... View the full answer