In the table below (Table 1), 3 different spherical polymeric compounds at certain time intervals
The experimentally measured cumulative effect of the drug (X) released from the particle (A, B, C)
concentration values are given. Pre-release polymeric particles of drug X
Their concentration in (Qo) is known as 13.476 mg/L.
a) Plot cumulative (mg/L) release graphs versus time
b) Depending on the experimental data in Table 1, all polymeric compounds of drugs
Evaluate the release mechanisms in particles by studying the Korsmeyer-Peppas, Higuchi and HixsonCrowell kinetic models
c) Determine the drug release kinetics of X for each delivery particle depending on the models.
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Table1. Time-dependent X drug concentration values (Qt)

n
 

 

Transcribed Image Text:

X İlacı Zaman (gün) PA3579135 0 11 A Kümülatif İlaç konsantrasyonu (mg/L) 0.000 0.703 0.974 1.112 1.209 1.279 1.335 1.381 1.410 B 0.000 1.194 1.817 2.221 2.497 2.704 2.863 2.991 3.091 C 0.000 3.244 4.992 5.876 6.500 6.900 7.058 7.287 7.461 X İlacı Zaman (gün) PA3579135 0 11 A Kümülatif İlaç konsantrasyonu (mg/L) 0.000 0.703 0.974 1.112 1.209 1.279 1.335 1.381 1.410 B 0.000 1.194 1.817 2.221 2.497 2.704 2.863 2.991 3.091 C 0.000 3.244 4.992 5.876 6.500 6.900 7.058 7.287 7.461

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a Plotting the cumulative mgL release graphs versus time Graph showing the cumulative drug release over time for the three polymeric compounds A B and ... View the full answer