Transmembrane Movement of Reducing Equivalents Under aerobic conditions, extramitochon- drial NADH must be oxidized by the...
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Transmembrane Movement of Reducing Equivalents Under aerobic conditions, extramitochon- drial NADH must be oxidized by the mitochondrial electron-transfer chain. Consider a preparation of rat hepatocytes containing mitochondria and all the cytosolic enzymes. If [4-HINADH is introduced, radioactivity soon appears in the mitochondrial matrix. However, if [7-4CJNADH is introduced, no radioactivity appears in the matrix. What do these observations reveal about the oxidation of extramito- chondrial NADH by the electron-transfer chain? 3H H NH [4-"HINADH HH NH [7-4 CINADH Transmembrane Movement of Reducing Equivalents Under aerobic conditions, extramitochon- drial NADH must be oxidized by the mitochondrial electron-transfer chain. Consider a preparation of rat hepatocytes containing mitochondria and all the cytosolic enzymes. If [4-HINADH is introduced, radioactivity soon appears in the mitochondrial matrix. However, if [7-4CJNADH is introduced, no radioactivity appears in the matrix. What do these observations reveal about the oxidation of extramito- chondrial NADH by the electron-transfer chain? 3H H NH [4-"HINADH HH NH [7-4 CINADH
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Fundamentals of biochemistry Life at the Molecular Level
ISBN: 978-0470547847
4th edition
Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt
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