Powdered dosage form can be formulated for medicines designed for different routes of administration such as Keflex
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Question:
Powdered dosage form can be formulated for medicines designed for different routes of administration such as Keflex (cefalexin monohydrate) powder for oral suspension and DBL™ Vancomycin (vancomycin hydrochloride) powder for infusion. Answer the following questions about these products.
- Discuss the rationale of formulating the drug cefalexin monohydrate as powder for oral suspension. [2 marks]
- The drug vancomycin hydrochloride in the product “DBL™ Vancomycin” is lyophilised. Explain the term “lyophilisation” and the need to prepare the drug in this form for this product. [2 marks]
- Explain the need to include the excipients in the product “Keflex (cefalexin monohydrate) powder for oral suspension”. Your answer should describe the function of each excipient and its suitability for this product. [4 marks]
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ISBN: 978-0324375589
6th Edition
Authors: larry e. rittenberg, bradley j. schwieger, karla m. johnston
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