Which group of students had a significant change in their own mean knowledge quiz score between the pretest and the first posttest?

It is really helpful to start reading professional research articles to see how these concepts are used in actual study scenarios. Give it a try in the following article, where the researchers used the t-test to analyze the relationship between clinical simulation methodologies and student learning. Scherer, Y., Foltz-Ramos, K., Fabry, D., & Chao, Y. (2016). Evaluating simulation methodologies to determine best strategies to maximize student learning. Journal of Professional Nursing, 32(5), 349–357.