1-Hetero-2,4-cyclopentadienes can be prepared by condensation of an -dicarbonyl compound and certain heteroatom-containing diesters. Propose a mechanism...

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1-Hetero-2,4-cyclopentadienes can be prepared by condensation of an α-dicarbonyl compound and certain heteroatom-containing diesters. Propose a mechanism for the following pyrrole synthesis.

H,C6, C,H5 00 NaOCH, CH,OH, д CH;CCC,H5 + CH;OCCH,NCH,COCH3 CH;OOC COOCH3 H;C H

How would you use a similar approach to synthesize 2,5-thiophenedicarboxylic acid?

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Organic Chemistry structure and function

ISBN: 978-1429204941

6th edition

Authors: K. Peter C. Vollhardt, Neil E. Schore

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Question Posted: May 12, 2020 04:30 AM

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1-Hetero-2,4-cyclopentadienes can be prepared by condensation of an -dicarbonyl compound and certain heteroatom-containing diesters. Propose a mechanism...

Question:

H,C6, C,H5 00 NaOCH, CH,OH, д CH;CCC,H5 + CH;OCCH,NCH,COCH3 CH;OOC COOCH3 H;C H

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Organic Chemistry structure and function

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