What is the justification for including extreme doses well outside the range of exposures encountered by people

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What is the justification for including extreme doses well outside the range of exposures encountered by people at risk in a dose–response study on animals of the effects of a hazardous substance? What are the problems with this approach?

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The Analysis Of Biological Data

ISBN: 9781319226237

3rd Edition

Authors: Michael C. Whitlock, Dolph Schluter

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