If a scientist was hoping to isolate and purify HAZL2, which of the following techniques would they
Question:
If a scientist was hoping to isolate and purify HAZL2, which of the following techniques would they use?
(A) Collect only the nuclear fraction
(B) Collect only the cytosolic fraction
(C) Collect only the extracellular fraction
(D) Collect only the lipid membrane fraction
Proteins often need the equivalent of a shipping label so that they can be sent intracellularly or extracellularly to the correct location. These labels are typically found in three forms: signal sequences, target signals, or localization signals. A signal sequence is a stretch of hydrophobic amino acid residue that is only located within polypeptides destined to fold into EITHER extracellular proteins, intermembrane proteins that will anchor to the cell surface, or proteins that will be members of the secretory pathway that packs and ships things towards the cell surface. A targeting signal is a sequence that identifies the proteins of the secretory pathway. A localization signal is a sequence that labels proteins that are destined to go to specific organelles (that are not part of the secretory pathway). The table below shows seven eukaryotic proteins, and the sequences have been identified in each.
Step by Step Answer:
The Princeton Review AP Biology Premium Prep 2023
ISBN: 9780593450659
2023 Edition
Authors: The Princeton Review