Suggest a synthesis of ibuprofen (Section 5.11) from benzene, employing chloromethylation as one step. Chloromethylation is a

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Suggest a synthesis of ibuprofen (Section 5.11) from benzene, employing chloromethylation as one step. Chloromethylation is a special case of the Friedel-Crafts reaction in which a mixture of HCHO and HCl, in the presence of ZnCl2, introduces a -CH2Cl group into an aromatic ring.
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Organic Chemistry

ISBN: 978-1118133576

11th edition

Authors: Graham Solomons, Craig Fryhle, Scott Snyder

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