Suppose that you were interested in investigating the effect of a drug that is to be used in the treatment of patients who have glaucoma in both eyes. A comparison between the mean reduction in eye pressure for this drug and for a standard treatment is desired. Both treatments are applied directly to the eye.
a. Describe how you would go about collecting data for your investigation.
b. Does your method result in paired data?
c. Can you think of a reasonable method of collecting data that would not result in paired samples? Would such an experiment be as informative as a paired experiment? Comment.