The aspirin substitute acetaminophen (C 8 H 9 O 2 N) is produced by the following three-step

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The aspirin substitute acetaminophen (C8H9O2N) is produced by the following three-step synthesis:

I. C6H5O3N(s) + 3H2(g) + HCl(aq) → C6H8ONCl(s) + 2H2O(l)

II. C6H8ONCl(s) + NaOH(aq) → C6H7ON(s) + H2O(l) + NaCl(aq)

III. C6H7ON(s) + C4H6O3(l) →C8H9O2N(s) + HC2H3O2(l)

The first two reactions have percent yields of 87% and 98% by mass, respectively. The overall reaction yields 3 moles of acetaminophen product for every 4 miles of C6H5O3N reacted.

a. What is the percent yield by mass for the overall process?

b. What is the percent yield by mass of step III?

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Chemical Principles

ISBN: 978-1111580650

7th edition

Authors: Steven S. Zumdahl, Donald J. DeCoste

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