The C-terminal end of a protein extends into the aqueous environment surrounding the protein. The C-terminal amino acids are Gln, Asp, 2 Ser, and three nonpolar amino acids. Assuming that ∆Go the for formation of a hydrogen bond is -3 kcal/mol and the for removal of a hydrophobic group from water is -4 kcal/mol, calculate the ∆G, for folding the C terminal end of the protein into the interior of the protein under the following conditions:
a. All the polar groups form one intramolecular hydrogen bond.
b. All but two of the polar groups form intramolecular hydrogen bonds.