The Knoevenagel reaction is a carbonyl condensation reaction of an ester with an aldehyde or ketone to
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The Knoevenagel reaction is a carbonyl condensation reaction of an ester with an aldehyde or ketone to yield an ?, ??un-saturated product. Show the mechanism of the Knoevenagel reaction of diethyl malonate with benzaldehyde.
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cO2Et H30+ HO. CH2(CO,Et)2 čO2Et Na+ "OEt, ethanol Cinnamic acid (91%) Benzaldehyde
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Formation of the enolate of diethyl malonate is the ...View the full answer
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