Question: The terms configuration and conformation appear in descriptions of molecular
The terms configuration and conformation appear in descriptions of molecular structure. How do they differ?
Answer to relevant QuestionsTheoretically, a protein could assume a virtually infinite number of configurations and conformations. Suggest several features of proteins that drastically limit the actual number. Describe the effect of 2,3-bisphosphoglycerate on the binding of oxygen by hemoglobin. Rationalize the following observations. (a) Serine is the amino acid residue that can be replaced with the least effect on protein structure and function. (b) Replacement of tryptophan causes the greatest effect on protein ...A mutation that changes an alanine residue in a protein to an isoleucine leads to a loss of activity. Activity is regained when a further mutation at the same site changes the isoleucine to a glycine. Why? With which amino acid sequences would chy-motrypsin be an effective reagent for sequencing the protein from Question 50? Why?
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