Using the information in Table 16.2, predict the product(s) of Table 16.2 Friedel-Crafts alkylation of a large
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Table 16.2
Friedel-Crafts alkylation of a large excess of ethylbenzene with chloromethane in the presence of A1C13.
Eq. 16.23
Transcribed Image Text:
TABLE 16.2 Deactivating Effects of Some Common Functional Groups Groups are listed in decreasing order of activation.) Substituent group Summary of Directing and Activating or Activating or deactivating Name of group Directing effect amino -OH hydroxy ーOR alkoxy 0 NH acylamino substituents ortho, para directors alkyl 0 acyloxy phenyl halogens 0 0 0 carboxy,carboxamido, carboalkoxy NH deactivating meta directors ac sulfonic acid cyano nitro SO H - CN acylium ion
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