What are the considerations for choice of a vector in gene therapy?
Answer to relevant QuestionsBoth ADA-SCID and type I diabetes are diseases based on lack of a particular protein. Why has the pioneering work on gene therapy focused on SCID instead of on diabetes? One of the first human proteins cloned was interferon. Why would it be important to be able to produce interferon in a lab? How are viruses related to cancer? Explain why some researchers believe science should focus its attention on the inflammation associated with cancer progression instead of looking for a cure. All the organophosphate compounds listed in Table 15.1 undergo hydrolysis reactions in the same way as ATP. The following equation illustrates the situation for glucose-1-phosphate. Glucose-1-phosphate + H2O → Glucose + ...
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