What are the similarities and differences between the re-actions catalyzed by pyruvate dehydrogenase and α-ketoglutarate dehydrogenase?
Answer to relevant QuestionsHow does substrate-level phosphorylation differ from phosphorylation linked to the electron transport chain? How does an increase in the NADH/NAD+ ratio affect the activity of pyruvate dehydrogenase? Recall Briefly summarize the steps in the electron transport chain from NADH to oxygen. Reflect and apply What are two advantages of the components of the electron transport chain being embedded in the inner mitochondrial membrane? Can an uncoupler of oxidative phosphorylation inhibit electron transport from one component of the electron transport chain to another? Why or why not?
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