Question: You are studying with a friend who is describing the
You are studying with a friend who is describing the Bohr effect. She tells you that in the lungs, hemoglobin binds oxygen and releases hydrogen ion; as a result, the pH increases. She goes on to say that in actively metabolizing muscle tissue, hemoglobin releases oxygen and binds hydrogen ion and, as a result, the pH decreases. Do you agree with her reasoning? Why or why not?
Answer to relevant QuestionsHow does the difference between the b-chain and the g-chain of hemoglobin explain the differences in oxygen binding between Hb A and Hb F? What is a prion? A mutation that changes an alanine residue in a protein to an isoleucine leads to a loss of activity. Activity is regained when a further mutation at the same site changes the isoleucine to a glycine. Why? Which enzymes or chemicals would you choose to use to cut the protein from Question 50? Why? What is proteomics?
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