(a) An aliphatic aminoglycoside is relatively stable to base, but it is quickly hydrolyzed by dilute acid....
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(b) Ribonucleosides are not so easily hydrolyzed, requiring relatively strong acid. Using your mechanism for part (a), show why cytidine and adenosine (for example) are not so readily hydrolyzed. Explain why this stability is important for living organisms.
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a b Nucleosides are less rapidly hydrolyzed in aqueous acid because the site of ...View the full answer
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