Alcohols undergo an oxidation reaction to yield carbonyl compounds on treatment with CrO₃. For example, 2-tert-butylcyclohexanol gives 2-tert-butylcyclo- hexanone. If axial ?OH groups are generally more reactive than their equatorial isomers, which do you think would react faster, the cis isomer of 2?tert?butylcvclohexanol or the trans isomer? Explain.

Transcribed Image Text:

HO Cro3 C(CH3)3 C(CH3)3 2-tert-Butylcyclohexanol 2-tert-Butylcyclohexanone