In oxygenated hemoglobin, pKa 5 6.6 for the histidines at position 146 on the b-chain. In deoxygenated

Question:

In oxygenated hemoglobin, pKa 5 6.6 for the histidines at position 146 on the b-chain. In deoxygenated hemoglobin, the pKa of these residues is 8.2. How can this piece of information be correlated with the Bohr effect?

Fantastic news! We've Found the answer you've been seeking!

Step by Step Answer:

Related Book For book-img-for-question

Biochemistry

ISBN: 978-1285429106

8th edition

Authors: Mary K. Campbell, Shawn O. Farrell

See More Books

Question Posted: Jul 08, 2015 12:12 PM

See More Questions

Oxygenated hemoglobin absorbs weakly in the red (hence its red color) and strongly in the near infrared, while deoxygenated hemoglobin has the opposite absorption. This fact is used in a pulse...
In the variant hemoglobin C, glutamate at position 6 of the chain has been replaced with lysine. (a) Would you expect this mutant hemoglobin to polymerize as hemoglobin S does? (b) Red blood cells...
How can a long piece of wire be wound on a spool so that the wire has a negligible self-inductance?
At the beginning of the current tennis season, on April 1, 2024, Kicked-Back Tennis Shops inventory consisted of 50 tennis racquets at a cost of $40 each. Kicked-Back uses a perpetual inventory...
If China wished to slow Starbucks expansion, what legal barriers would be most helpful? How would these barriers affect Chinese consumers and businesses?
The following is the ending balances of accounts at December 31, 2016 for the Valley Pump Corporation. Additional Information: 1. The $120,000 balance in the land account consists of $100,000 for the...
Sketch and describe the magnetic poles of a spherical piece of uniformly magnetized material.
Bandung Corporation began 2008 with a $92,000 balance in the Deferred Tax Liability account. At the end of 2008, the related cumulative temporary difference amounts to $350,000, and it will reverse...
Handshake owns and manages a small manufacturing business in Narok town. The following balances have been extracted from his books of account at 31 December 2018: Dr Cr Sh. Sh. Capital 1,711,200...
What is the hydrologic cycle? What are the pathways that precipitation falling onto the land surface of the Earth is dispersed to the hydrologic cycle?
Describe the effect of 2,3-bisphosphoglycerate on the binding of oxygen by hemoglobin.
You are studying with a friend who is describing the Bohr effect. She tells you that in the lungs, hemoglobin binds oxygen and releases hydrogen ion; as a result, the pH increases. She goes on to say...
Our spy, intent on avenging the death of Siggy Leiter (Exercise 75 in Section 4.2), is driving a sports car toward the lair of the fiend who killed his friend. To remain as inconspicuous as possible,...
what is your strength and weakness and how do you manage it?
Brief the terry v Ohio and Miranda v Arizona cases. also describe APA paraphrase Title Facts Issues Decisions Reasoning Dissenting opinions ?
What does state and federal legislation have to do with AHIMA Code of Ethics?
What is a period cost for a company that manufactures baby car seats?
What account(s) is/are credited when a production job is completed? Explain with example.
In the xy-plane, a parabola with the equation y = (x + 3) 2 + 9 intersects a line with the equation y = -7 at two points, P and Q. What is the length of PQ?
Figure displays a 12.0 V battery 3 four uncharged capacitors of capacitances C1 = 4.00F, C2 = 6.00F, and C3 = 3.00F. The switch is thrown to the left side until capacitor 1 is fully charged. Then the...
Rationalize the following observations. (a) Serine is the amino acid residue that can be replaced with the least effect on protein structure and function. (b) Replacement of tryptophan causes the...
What is a prion?
What are the known diseases caused by abnormal prions?
A project costs $80 MM, with 25% of the investment int in year 1 and the balance in year 2. The plant operates atates at 50% capacity in year 3 and then full capacity for the next next 20 years. The...
What is organizational Behaviour the study of? How is social sciences related to organizational behavior? What is the difference between social science and organizational behavior? What is the...
Describe the nature of organization change, including forces for change and planned versus reactive change

In oxygenated hemoglobin, pKa 5 6.6 for the histidines at position 146 on the b-chain. In deoxygenated

Question:

Step by Step Answer:

Deoxygenated hemoglobin is a weaker acid has a higher pK a th...View the full answer

Biochemistry

Students also viewed these Medical Sciences questions