Rationalize the following observations. (a) Serine is the amino acid residue that can be replaced with the
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(a) Serine is the amino acid residue that can be replaced with the least effect on protein structure and function.
(b) Replacement of tryptophan causes the greatest effect on protein structure and function.
(c) Replacements such as Lys S Arg and Leu S Ile usually have very little effect on protein structure and function.
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