Staphylococcus nuclease is an enzyme that catalyzes the hydrolysis of DNA. The overall hydrolysis reaction is as

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Staphylococcus nuclease is an enzyme that catalyzes the hydrolysis of DNA. The overall hydrolysis reaction is as follows:

Recall that the nucleotides in DNA have phosphodiester linkages. The reaction is catalyzed by Ca2+, Glu 43, and Arg 87. Propose a mechanism for this reaction.

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Organic Chemistry

ISBN: 978-0131407480

4th edition

Authors: Paula Yurkanis Bruice

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Question Posted: Jun 10, 2016 07:49 AM

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Staphylococcus nuclease is an enzyme that catalyzes the hydrolysis of DNA. The overall hydrolysis reaction is as

Question:

RO-р —Он + RO-P-OR Н.о + ROH

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A possible mechanism for hydrolysis of the phospho...View the full answer

Organic Chemistry

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