Suppose that we are fitting a straight line and we desire to make the variance of A

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Suppose that we are fitting a straight line and we desire to make the variance of A as small as possible. Restricting ourselves to an even number of experimental points, where should we place these points so as to minimize V(β̂1)? Use the design called for in this exercise with great caution because, even though it minimizes V(β̂1), it has some undesirable properties; for example, see Myers and Montgomery (1995). Only if you are very sure the true functional relationship is linear should you consider using this design.

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