In a test of the effectiveness of garlic for lowering cholesterol, 47 subjects were treated with Garlicin, which is garlic in a processed tablet form. Cholesterol levels were measured before and after the treatment. The changes in their levels of LDL cholesterol (in mg dL) have a mean of 3.2 and a standard deviation of 18.6 (based on data from “Effect of Raw Garlic vs Commercial Garlic Supplements on Plasma Lipid Concentrations in Adults With Moderate Hypercholesterolemia,” by Gardner et al., Archives of Internal Medicine, Vol. 167).

a. What is the best point estimate of the population mean net change in LDL cholesterol after the Garlicin treatment?

b. Construct a 95% confidence interval estimate of the mean net change in LDL cholesterol after the Garlicin treatment. What does the confidence interval suggest about the effectiveness of Garlicin in reducing LDL cholesterol?

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