Describe the typical principles used to identify topogenic sequences within proteins and how these can be used
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Describe the typical principles used to identify topogenic sequences within proteins and how these can be used to develop computer algorithms. How does the identification of topogenic sequences lead to prediction of the membrane arrangement of a multipass protein? What is the importance of the arrangement of positive charges relative to the membrane orientation of a signal-anchor sequence?
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Many membrane proteins are embedded in the membrane by virtue of transmembrane ahelical segments Suc...View the full answer
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Related Book For
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
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