Microinjection of an antibody known as EAGE, which reacts with the hinge region of the subunit
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Microinjection of an antibody known as EAGE, which reacts with the "hinge" region of the β subunit of COPI, causes accumulation of Golgi enzymes in transport vesicles and inhibits anterograde transport' of newly synthesized vesicles from the ER to the plasma membrane. What effect does the antibody have on COPI activity? Explain the results.
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Coat proteins must assemble onto a membrane to form a vesicle and must disassemble to allow the v...View the full answer
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Related Book For 
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
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