Most mammalian cells have a single immobile cilium called the primary cilium, in which intraflagellar transport (1FT)
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Most mammalian cells have a single immobile cilium called the primary cilium, in which intraflagellar transport (1FT) microtubule motor proteins move elements of the Hedgehog (Hh) signaling pathway. What parts of the Hh signaling pathway would mutations in the IFT motor proteins Kif3A, Kif7, and dynein disrupt?
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When Hh activates the Patched receptor Smoothened Smo is phosphorylated by b...View the full answer
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Related Book For 
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
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