Signal-transducing trimeric G proteins consist of three subunits designated , and ' The G a subunit

Signal-transducing trimeric G proteins consist of three subunits designated α, β and 'γ· The G_a subunit is a GTP_ase switch protein that cycles between active and inactive states depending on whether it is bound to GTP or to GDP. Review the steps for ligand-induced activation of effector proteins mediated by the trimeric G proteins. Suppose that you have isolated a mutant G_a subunit that has an increased GTP_ase activity. What effect would this mutation have on the G protein and the effector protein?