What do LDL receptor (LDLR) cytoplasmic domain mutations that cause familial hypercholesterolemia reveal about the receptor-mediated endocytosis

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What do LDL receptor (LDLR) cytoplasmic domain mutations that cause familial hypercholesterolemia reveal about the receptor-mediated endocytosis (RME) pathway?

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Molecular Cell Biology

ISBN: 978-1429234139

7th edition

Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott

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Question Posted: Apr 16, 2018 09:33 AM

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What do LDL receptor (LDLR) cytoplasmic domain mutations that cause familial hypercholesterolemia reveal about the receptor-mediated endocytosis

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The mutant LDLRs bind LDL normally but only randomly get internalized in...View the full answer

Molecular Cell Biology

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