What features of the dynactin complex enable cytoplasmic dynein to transport cargo toward the microtubule (-) end?

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What features of the dynactin complex enable cytoplasmic dynein to transport cargo toward the microtubule (-) end? What effect could inhibition of dynactin interactions with the +TIP EB-1 have on spindle orientation in cells?

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Molecular Cell Biology

ISBN: 978-1429234139

7th edition

Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott

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Question Posted: Apr 17, 2018 07:55 AM

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What features of the dynactin complex enable cytoplasmic dynein to transport cargo toward the microtubule (-) end?

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The dynactin complex links cytoplasmic dynein to cargo The weak microtu...View the full answer

Molecular Cell Biology

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