In E. coli, viable polA mutants have been isolated that produce a defective gene product with little
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In E. coli, viable polA mutants have been isolated that produce a defective gene product with little or no 5′→3′ polymerase activity, but normal 5′→3′ exonuclease activity. However, no polA mutant has been identified that is completely deficient in the 5′→3′ exonuclease activity, while retaining 5′→3′ polymerase activity, of DNA polymerase I. How can these results be explained?
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Principles of Genetics
ISBN: 978-1119142287
7th edition
Authors: D. Peter Snustad, Michael J. Simmons
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