The gene for a-globin is present in all vertebrate species. Over millions of years, the DNA sequence

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The gene for a-globin is present in all vertebrate species. Over millions of years, the DNA sequence of this gene has changed in the lineage of each species. Consequently, the amino acid sequence of a-globin has also changed in these lineages. Among the 141 amino acid positions in this polypeptide, human a-globin differs from shark a-globin in 79 positions; it differs from carp a-globin in 68 and from cow a-globin in 17. Do these data suggest an evolutionary phylogeny for these vertebrate species?

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Principles of Genetics

ISBN: 978-1119142287

7th edition

Authors: D. Peter Snustad, Michael J. Simmons

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