The relationship between the melting T m and GC content can be expressed, in its much simplified
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The relationship between the melting Tm and GC content can be expressed, in its much simplified form, by the formula Tm = 69 + 0.41 (% GC).
(a) Calculate the melting temperature of E. coli DNA that has about 50% GC.
(b) Estimate the %GC of DNA from a human kidney cell where Tm = 85°C.
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Related Book For
Principles of Genetics
ISBN: 978-1119142287
7th edition
Authors: D. Peter Snustad, Michael J. Simmons
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