We discussed the unfortunate effects of insertional mutagenesis in the four boys who developed leukemia after treatment

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We discussed the unfortunate effects of insertional mutagenesis in the four boys who developed leukemia after treatment of X-linked severe combined immunodeficiency disease by gene therapy. How might this consequence of gene therapy be avoided in the future? Do you believe that the use of somatic-cell gene therapy to treat human diseases can ever be made 100 percent risk-free? Why? Why not?

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Principles of Genetics

ISBN: 978-1119142287

7th edition

Authors: D. Peter Snustad, Michael J. Simmons

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