Consider a ribosome translating a codon to an amino acid. Compared to a perfect pairing, imagine that
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Question:
Consider a ribosome translating a codon to an amino acid. Compared to a perfect pairing, imagine that a codon-anticodon paring with one incorrect base pair is 10 kJ/mol higher in energy, two incorrect base pairs is 20 kJ/mol higher, and three incorrect base pairs is 30 kJ/mol higher.
How many ways are there of making a one-, two-, or three-base-pair mismatch? What is the partition function of the codon-anticodon system at 300 K? If energy difference is the only consideration, what percent of decoding events occur with an error (no mismatches) at 300 K?
Related Book For
Chemistry The Central Science
ISBN: 978-0321696724
12th edition
Authors: Theodore Brown, Eugene LeMay, Bruce Bursten, Catherine Murphy, Patrick Woodward
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