Show how the Hell-Volhard-Zelinsky reaction might be used in the synthesis of each of the following compounds,
Question:
Show how the Hell-Volhard-Zelinsky reaction might be used in the synthesis of each of the following compounds, beginning in each case with a simple monocarboxylic acid. Write detailed mechanisms for all the reactions in one of your syntheses.
(a)
(b)
(c)
(d) HO2CCH2SSCH2CO2H
(e) (CH3CH2)2NCH2CO2H
(f)
Transcribed Image Text:
CH;CH,CHCO,H NH,
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Solution HellVolhard Zelinsky reaction a Mechanism b NH c OH CH OH 1PBr 1 equ Br ...View the full answer
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Mohd Rehan
I teach in a local coaching centre for 4 years in Aligarh India. I am pursuing PhD from AMU Aligarh. I am all India qualified tests NET (National Eligibility Test) and GATE. Four certificates from NPTEL (1) Medicinal chemistry from IISER Pune, (2) Retrosynthesis from IIT Kharagpur (3) Application of NMR from IISc Bangalore, (4) Multidimensional NMR from IISc Bangalore. Eight research articles have been published in the chemistry field.
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Related Book For
Organic Chemistry structure and function
ISBN: 978-1429204941
6th edition
Authors: K. Peter C. Vollhardt, Neil E. Schore
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