The rate of the reaction of NH2OH with aldehydes and ketones is very sensitive to pH. It

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The rate of the reaction of NH2OH with aldehydes and ketones is very sensitive to pH. It is very low in solutions more acidic than pH 2 or more basic than pH 7. It is highest in moderately acidic solution (pH ∼ 4). Suggest explanations for these observations.

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Organic Chemistry structure and function

ISBN: 978-1429204941

6th edition

Authors: K. Peter C. Vollhardt, Neil E. Schore

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