The enzymatic introduction of a functional group into a biologically important molecule is not only specific with
Question:
(a) Is the configuration of (-) norepinephrine R or S?
(b) In the absence of an enzyme, would the transition states of a radical oxidation leading to (-)- and (+)-norepinephrine be of equal or unequal energy? What term describes the relation between these transition states
(c) In your own words, describe how the enzyme must affect the energy of these transition states to favor production of the (-) enantiomer. Does the enzyme have to be chiral or can it be achiral?
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Related Book For
Organic Chemistry structure and function
ISBN: 978-1429204941
6th edition
Authors: K. Peter C. Vollhardt, Neil E. Schore
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