The enzyme carbonic anhydrase catalyzes the reaction CO2(g) + H2O(l) HCO3(aq) + H+(aq). In water, without

The enzyme carbonic anhydrase catalyzes the reaction CO2(g) + H2O(l) → HCO3ˉ(aq) + H+(aq). In water, without the enzyme, the reaction proceeds with a rate constant of at 25 oC. In the presence of the enzyme in water, the reaction proceeds with a rate constant of 1.0 × 106 s-1 at 25 oC. Assuming the collision factor is the same for both situations, calculate the difference in activation energies for the un-catalyzed versus enzyme-catalyzed reaction?