An Fmoc protecting group can be removed from an amino acid by treatment with the amine base

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An Fmoc protecting group can be removed from an amino acid by treatment with the amine base piperidine. Propose amechanism.

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Organic Chemistry

ISBN: 9780495112587

7 Edition

Authors: John McMurry

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Question Posted: Mar 08, 2011 05:48 AM

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An Fmoc protecting group can be removed from an amino acid by treatment with the amine base

Question:

pKg = 23 !! CH2 -NHCHCO- HoiçHdo- NaOH H3NCHCO- Co2 Н2о Fmoc-protected amino acid

Step by Step Answer:

H CO NHCHCO R HNCHCO HO R 2 CH NHCHCO Compet R HOH Step ...View the full answer

Organic Chemistry

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