We saw in Section 17.4 that ketones react with NaBH 4 to yield alcohols. We?ll also see
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We saw in Section 17.4 that ketones react with NaBH4 to yield alcohols. We?ll also see in Section 22.3 that ketones react with Br2 to yield a-bromo ketones. Perhaps surprisingly, treatment with NaBH4 of the a-bromo ketone from acetophenone yields an epoxide rather than a bromo alcohol. Show the structure of the epoxide, and explain its formation.
Transcribed Image Text:
CH2BR NABH Ерохide CH3 Br2 An a-bromo ketone Acetophenone
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