Each of the following reactions has been reported in the chemical literature and gives a predominance of
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CO2H OCH Cl H,so, H:504. hent CO,H CH3 CFT H3C OH Br CH2 CH acetic acid CHC H-NNH, KOH triethylena elyool, 173 C CHO C(CH3 AICH F + CH2CI> acetic acid CHCH)2 CH CNH CH2CH H SOA 5-15 C + CH,CCI 0 AIC Zn(Hg H,C CH, (CH2 CO-H acetic acid NO2
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a Nitration of the ring takes place para to the ortho paradirecting chlorine substituent this position is also meta to the metadirecting carboxyl groups b Bromination of the ring occurs at the only av...View the full answer
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