Analysis of p53 gene mutations in human tumors shows that a large proportion of these mutations involve

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Analysis of p53 gene mutations in human tumors shows that a large proportion of these mutations involve GC → AT transitions originating at sites of DNA methylation. Propose a model to explain preferential mutagenesis of this type at these sites.

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Biochemistry Concepts And Connections

ISBN: 9780134641621

2nd Edition

Authors: Dean Appling, Spencer Anthony-Cahill, Christopher Mathews

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Question Posted: Nov 06, 2023 03:18 AM

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Analysis of p53 gene mutations in human tumors shows that a large proportion of these mutations involve

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Model to explain preferential mutagenesis of GC AT transitions at sites of DNA methylation in the p53 gene in human tumors 1 Methylation of cytosine r...View the full answer

Biochemistry Concepts And Connections

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