Gemcitabine is a deoxycytidine analog used in treating pancreatic and ovarian cancer. The drug requires metabolic activation
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Gemcitabine is a deoxycytidine analog used in treating pancreatic and ovarian cancer. The drug requires metabolic activation after uptake into cells. Speculate on the pathway for activation and the identity of the target enzyme.
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Gemcitabine is a prodrug that requires metabolic activation within cells to exert its cytotoxic effe...View the full answer
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Related Book For 
Biochemistry Concepts And Connections
ISBN: 9780134641621
2nd Edition
Authors: Dean Appling, Spencer Anthony-Cahill, Christopher Mathews
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