Starting with an equimolar mixture of acetaldehyde and NAD⁺ at 25°C, calculate and plot the extent of the following reaction as a function of pH. Also determine the pH at which half the acetaldehyde will have reacted at equilibrium.

For this reaction at solution conditions, the apparent Gibbs energy change is Δ_rxnG = 50.2 kJ. Also, assume that water is present in great excess, so that its concentration does not change in the course of the reaction.

Transcribed Image Text:

CH3CHO + NAD+ + H₂O -> CH3CO₂ + NADH + 2H+ acetaldehyde acetate