Estimate the effective pore diffusivity, , of a monoclonal antibody in a water-saturated porous particle with porosity
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Estimate the effective pore diffusivity, , of a monoclonal antibody in a water-saturated porous particle with porosity = 0.60 at20°C. The pore radius is = 20 nm and the tortuosity factor is = 2.0.The diffusivity of the protein in water can be estimated from the Tyn &
Gusek equation. The radius of the protein can be estimated from this diffusivity value using the Stokes–Einstein equation. The monoclonal antibody is a globular protein with molecular mass 150,000.
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Heat And Mass Transfer For Chemical Engineers Principles And Applications
ISBN: 9781264266678
1st Edition
Authors: Giorgio Carta
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