Look carefully at Figure 6−11 and at the structures of the compounds shown in Figure Q6−9.

A. What would you expect if ddCTP were added to a DNA replication reaction in large excess over the concentration of the available dCTP, the normal deoxycytidine triphosphate?

B. What would happen if it were added at 10% of the concentration of the available dCTP?

C. What effects would you expect if ddCMP were added under the same conditions?

Figure Q6−9

Figure Q6−11

Transcribed Image Text:

Figure Q6-9 deoxycytidine triphosphate (dCTP) OH P -CH₂ -CH₂ P-O-CH₂ dideoxycytidine triphosphate (ddCTP) NH₂ NH₂ NH₂ dideoxycytidine monophosphate (ddCMP)