A new drug is to have the formula para-CH 3 CH 2 -(C 6 H 4 )-CH
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A new drug is to have the formula para-CH3CH2-(C6H4)-CH2CH2COOH, where (C6H4) designates a phenyl ring. A useful method for assessing the extent of partitioning between the bloodstream and body fat is to determine the infinite dilution partitioning coefficient for the drug between water and n-octanol. Use UNIFAC to make this determination. The body temperature is 37°C. Will the new drug stay in the bloodstream or move into fatty body parts?
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Related Book For
Introductory Chemical Engineering Thermodynamics
ISBN: 9780136068549
2nd Edition
Authors: J. Elliott, Carl Lira
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